Chronic obstructive pulmonary disease

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The clinical case of Mr. Charles Davis

A 60-year-old male patient goes to his general practitioner because he wants to start exercising on a regular basis. He refers productive cough in the mourning and dyspnoea for intense efforts for 2 years.
He recently has had one episode of flu like symptoms, although he had been treated with antibiotics. A chest X-ray has been reported as normal.
On physical exam bilateral wheezing and expiratory time prolongation are noted. He is a non-smoker but is exposed to tabaco smoke in his work.
No other relevant previous medical records.

Learning goals

  • COPD diagnosis
  • COPD classification and stratification


  1. Treatment plan

Key medicines

  • Short-acting beta2 agonists (SABAs)
  • Long-acting beta2 agonists (LABAs)
  • Short-acting antimuscarinic antagonists (SAMAs)
  • Long-acting antimuscarinic antagonists (LAMAs)
  • Inhaled corticosteroids (ICS)
  • Phosphodiesterase-4 (PDE4) inhibitors
  • Mucolytics


  • Golden Initiative for Chronic Obstructive Lung Disease. Golden Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease (2021 Report). 2021.

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